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Single-cell RNA sequencing data of primary and super-charged NK cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE226160
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NK cells are essential for mediating host immune responses. Approaches to augmenting the immunosurveillance function of NK cells have been extensively studied. Based on multiple publications, super-charged NK cells have been shown to be successfully activated with enhanced cytokine production and cytotoxicity capabilities. Here we use the single-cell RNA sequencing technique to understand the transcriptomic differences between IL-2 cultured and super-charged NK cells. Our data will help improve our understanding of applying NK cells for immunotherapy. Single-cell RNA sequencing analyses of IL-2 cultured and super-charged NK cells derived from the PBMC of healthy donors.
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2025-04-17
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