Genes and polymorphism identification associated to umbilical hernias in swine. Sus scrofa breed:Landrace

Umbilical hernia (UH) is one of the most frequent defects affecting pig production, however, it also affects humans and other mammals. UH is characterized as an abnormal protrusion of the abdominal contents to the umbilical region, causing pain, discomfort and reduced performance in pigs. Some genomic regions associated to UH have already been identified, however, no study involving RNA and exome sequencing has been performed trying to dissect the molecular mechanisms involved with this condition. Therefore, here, we have sequenced the umbilical ring transcriptome and exome of five normal and five UH-affected pigs to uncover genes and pathways involved with UH development.