Torpedo californica AChE in complex with indolic multi-target directed ligand
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6ezg
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Torpedo californica AChE in complex with indolic multi-target directed ligand Descriptor: 1-(7-chloranyl-4-methoxy-1~{H}-indol-5-yl)-3-[1-(phenylmethyl)piperidin-4-yl]propan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... Authors: Santoni, G, Lalut, J, Karila, D, Lecoutey, C, Davis, A, Nachon, F, Sillman, I, Sussman, J, Weik, M, Maurice, T, Dallemagne, P, Rochais, C. Deposit date: 2017-11-15 Release date: 2018-11-21 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Novel multitarget-directed ligands targeting acetylcholinesterase and sigma1receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase. Eur J Med Chem, 162, 2018
创建时间：
2017-11-15
