GNPS - Metabolomics unveils disrupted pathways in Parkinson's disease: towards biomarker-based diagnosis

Traditional clinical observation methods often result in misdiagnosis, highlighting the need for biomarker-based diagnostic approaches. This study utilizes UPLC-ESI-QTOF untargeted metabolomics combined with biochemometrics to identify novel serum biomarkers for PD. Analyzing a Brazilian cohort of serum samples from 39 PD patients and 15 healthy controls, we identified fifteen metabolites significantly associated with PD