Crystal structure of ULK1 kinase domain with inhibitor MR-2088
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Crystal structure of ULK1 kinase domain with inhibitor MR-2088 Descriptor: (4P)-4-[(2P)-2-(1,2,5,6-tetrahydropyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N-(2,2,2-trifluoroethyl)thiophene-2-carboxamide, 1,2-ETHANEDIOL, SULFATE ION, ... Authors: Schonbrunn, E, Sun, L. Deposit date: 2023-05-15 Release date: 2024-03-27 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Development of potent and selective ULK1/2 inhibitors based on 7-azaindole scaffold with favorable in vivo properties. Eur.J.Med.Chem., 266, 2024
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2023-05-15
