Table S1 - The Transcriptome of the Nosocomial Pathogen <em>Enterococcus faecalis</em> V583 Reveals Adaptive Responses to Growth in Blood

Microarray expression data from E. faecalis strain V583 during incubation in blood or 2xYT supplemented with 10% blood (YTB). Gene expression after 30 minutes (blood) or 5, 15, 30 and 60 minutes (YTB) of incubation is relative to the expression during growth in 2xYT for the corresponding time length. a) Genes comprising putative operon structures predicted by http://biocyc.org [1], [2] are marked with one color (red or light red for genes on the leading strand, blue or light blue for genes in on the lagging strand). b) Log2-values greater than 1 or less than -1 are highlighted in red or green respectively. Genes for which less than 8 spots were present were discarded from the analysis and are denoted “NA”. c) A significantly regulated gene (bonferroni corrected level of p<0.05) has the corresponding p-value written in bold. 1.Paley SM, Karp PD (2002) Evaluation of computational metabolic-pathway predictions for Helicobacter pylori. Bioinformatics 18: 715–724. 2. Romero PR, Karp PD (2004) Using functional and organizational information to improve genome-wide computational prediction of transcription units on pathway-genome databases. Bioinformatics 20: 709–717. (0.34 MB PDF)