Crystal structure of human heparanase in complex with covalent inhibitor VL166
收藏Protein Data Bank Japan2024-11-20 更新2026-03-28 收录
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Crystal structure of human heparanase in complex with covalent inhibitor VL166 Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-(2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Wu, L, Armstrong, Z, Davies, G.J. Deposit date: 2021-09-21 Release date: 2022-08-03 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
创建时间:
2021-09-21



