How an ABO-incompatible graft may improve its survival by phenotype-specific glycosylation of the host. A hypothesis.

In contrast to non-nucleated ABO-incompatible red cells, which from a HLA-compatible donor are transfused to a blood group O(H) recipient and undergo immediate destruction, a nucleated, metabolic active tissue that from the same donor is transplanted to the same recipient may, taking into account the effect of all therapeutic measures, show extreme long survival times. <br> <br>