Epicardial Adipose Tissue Thickness Associated with Preeclampsia and Birth Weight in Early Pregnancy

This was a single-center retrospective study, 221 patients with PE were selected, and 81 women without hypertension and proteinuria were selected as a comparison. Echocardiographic was used to measure the thickness of EAT. EAT thickness was significantly elevated (6.60±1.34 vs. 5.71±1.79 mm, p < 0.001) in severe PE compared to mild PE. In the multivariate analysis, EAT thickness (OR 5.671, 95% CI, 1.991-16.150, p = 0.001), and hypersensitive C reactive protein (OR 4.097, 95% CI, 2.323-7.224, p<0.001) were found as significant independent predictors of severe PE after adjusting for other risk factors. Linear regression analysis showed that hs-CRP, EAT thickness, and severe PE significantly negatively affected birth weight.