Gm364 Coordinates MIB2/DLL3/Notch2 to Regulate Female Fertility through AKT Activation

<strong>Supplementary dataset 1. </strong>Related to fertility assays in Figure 1I and 1J. WT mating male mice were monthly rotated between cages according to this random allocation table. Dates are presumptive. <strong>Supplementary </strong><strong>dataset</strong> <strong>2</strong><strong>.</strong> Related to figure 7A-C. This excel file contains FPKM values of three WT or Gm364-KO repeats, Log2-Ave value, and Log2(Ave-Gm364-KO/ave-WT) for each genes. To avoid the illegal calculation of value “0”, we added a minimal value “0.001” to all original values (we have verified that this did not alter any differential trends). The data were arranged to the ascending order of Log 2(Ave-Gm364-KO/ave-WT) values. <strong>Supplementary </strong><strong>dataset</strong> <strong>3</strong><strong>.</strong> Related to figure 7D and 7E. This excel file contains six sheets. "CPG-all info", "CHG-all info", and "CHH-all info" contain all original information for CPG, CHG, or CHH promoter regions of each genes; "CpG methyl value", "CHG methyl value", and "CHH methyl value" contain methylation values, Ave methylation values of three WT or Gm364-KO repeats, Log2-Ave value, and Log2(Ave-Gm364-KO/ave-WT) for CPG, CHG, or CHH promoter regions of each genes. To avoid the illegal calculation of value “0”, we added a minimal value “0.001” to all original values (we have verified that this did not alter any differential trends). The data were arranged to the ascending order of Log 2(Ave-Gm364-KO/ave-WT) values. <strong>Supplementary dataset 4. </strong>Related to figure 8A and 8G. This excel file contains two sheets. "RNA seq up &amp; down top 20" contains top 20 up-regulated &amp; down-regulated DEGs; "RRBS up &amp; down top 20" contains top 20 up-regulated &amp; down-regulated DMRs.