Msx2

ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding (ortholog); INVOLVED IN cartilage development; osteoblast development; positive regulation of apoptotic process; ASSOCIATED WITH Femoral Fractures; hypertension; Craniofacial Abnormalities (ortholog); FOUND IN cytosol (ortholog); nuclear speck (ortholog); transcription regulator complex (ortholog); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 2,6-dinitrotoluene; 3,7-dihydropurine-6-thione

编码一种展现DNA结合转录因子活性的蛋白质，特异性地作用于RNA聚合酶II；特异性地结合RNA聚合酶II顺式调控区序列的DNA；DNA结合（同源）；参与软骨发育；成骨细胞发育；凋亡过程的正向调控；与股骨骨折、高血压、颅面畸形（同源）相关；存在于细胞质（同源）、核斑（同源）、转录调控复合体（同源）；与1-[(4-氯苯基)-苯甲基]-4-甲基吡嗪、2,6-二硝基甲苯、3,7-二氢嘌呤-6-硫酮相互作用。