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Crystal structure of human prolyl-tRNA synthetase in complex with inhibitor

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Protein Data Bank Japan2025-09-17 更新2026-04-19 收录
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Crystal structure of human prolyl-tRNA synthetase in complex with inhibitor Descriptor: (2~{S})-~{N}-[3-(4-azanylquinazolin-7-yl)phenyl]sulfonylpyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, Bifunctional glutamate/proline--tRNA ligase Authors: Luo, Z, Zhou, H. Deposit date: 2024-03-26 Release date: 2025-04-02 Last modified: 2025-09-17 Method: X-RAY DIFFRACTION (2.553 Å) Cite: Development of potent inhibitors targeting bacterial prolyl-tRNA synthetase through fluorine scanning-directed activity tuning. Eur.J.Med.Chem., 291, 2025
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2024-03-26
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