DCN1 bound to inhibitor 10
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DCN1 bound to inhibitor 10 Descriptor: Lysozyme, DCN1-like protein 1 chimera, N-[(1S)-1-cyclohexyl-2-{[(2S)-3-(1H-imidazol-1-yl)-2-methylpropanoyl]amino}ethyl]-N~2~-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alaninamide Authors: Stuckey, J.A. Deposit date: 2020-07-07 Release date: 2021-06-02 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity. Nat Commun, 12, 2021
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2020-07-07
