five

Genome-wide expression of mRNAs and microRNAs in response to ERI2 knockdown

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE100610
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资源简介:
Here we describe the biological properties of new member of the Enhancer of RNAi (ERI) subfamily of DEDDh nucleases in humans, called ERI-2 that is important for miRNA processing and decay for a large subset of eukaryotic miRNA transcripts. hERI-2 is a potent Mg2+ dependent 3’-5’ exoribonuclease that also regulates the cell cycle and is a negative regulator of RISC. miRNA-seq and RNA-seq in ERI2 KD and control samples
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2020-06-01
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