Frequency and clinical significance of histologic upper gastrointestinal tract findings in children with inflammatory bowel disease

Assessment of the upper gastrointestinal tract (UGI) may enable more personalized treatment strategies in pediatric inflammatory bowel disease (IBD). However, data on the frequency and significance of these findings remain limited. Data on 132 pediatric IBD patients with systematic UGI sampling were collected and the baseline characteristics and presence of complications compared between those with and without histological UGI findings. The control group comprised 162 children who received no diagnoses. Seventy-six children had ulcerative colitis (UC), 47 Crohn’s disease (CD) and nine IBD unclassified. UGI findings were more common in IBD patients than controls (69.7% vs. 30.9%, respectively, p

对上消化道（UGI）的评估可能有助于在儿童炎症性肠病（IBD）中制定更为个性化的治疗方案。然而，关于这些发现频率及重要性的数据仍然有限。收集了132名具有系统上消化道采样的儿童IBD患者的数据，并比较了具有与不具有组织学上消化道发现的患者之间的基线特征和并发症的发生情况。对照组包括162名未接受诊断的儿童。其中，76名患有溃疡性结肠炎（UC），47名患有克罗恩病（CD）和9名未分类IBD。与对照者相比，IBD患者上消化道发现更为常见（分别为69.7%和30.9%，p