Predicted structures in FoxD proteins.

Legend: The N-terminus of each FoxD protein contains the conserved IDVV/IDIL/IDVL sequence at the amino acid (aa) location indicated, closely followed by a glycine (G) residue. Psipred predicts these regions to be random coil, whereas Porter predicts most of them to form a β-strand at the amino acids indicated. The C-terminus of each FoxD protein contains a conserved Eh-1 motif at the amino acid (aa) location indicated. At locations downstream of this motif, the proteins are predicted to either be random coil or to form an α-helical structure at the indicated locations.