Additional file 3: Table S2. of The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations

Location of putative phosphorylation sites within the endonuclease domain of L1 ORF2. Putative protein phosphorylation sites within the ORF2 endonuclease domain were identified using the ELM prediction tool [37] and NetPhos 2.0 phosphorylation prediction program [38]. The ELM p-value is a conservative estimate of the probability that an ELM prediction with a given score is a true positive. The significance cut-off is 10e-2. The NetPhos output score is a value in the range of 0.000â 1.000 (the higher the score, the higher the confidence of the prediction). (XLSX 10Â kb)