Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and DAB at 37 degrees Celsius

Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and DAB at 37 degrees Celsius Descriptor: 4,4'-[(pyridin-2-yl)methylene]diphenol, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4 Authors: Jinhong, H, Wei, L, Juan, D. Deposit date: 2025-08-31 Release date: 2026-02-04 Last modified: 2026-02-18 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Noncanonical calcium-independent TRPM4 activation governs intestinal fluid homeostasis. Nat Commun, 17, 2026