Plasmodium falciparum assocation study of artemisinin resistance
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Plasmodium falciparum assocation study of artemisinin resistance
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2014-05-28
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Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance
Successful control of falciparum malaria depends greatly on treatment with artemisinin combination therapies. Thus, reports that resistance to artemisinins (ARTs) has emerged, and that the prevalence
NIAID Data Ecosystem80
Double mutant (A16V+S108T) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS-T9/94) complexed with pyrimethamine, NADPH, and dUMP
Double mutant (A16V+S108T) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS-T9/94) complexed with pyrimethamine, NADPH, and dUMP Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHA
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The P. falciparum UDP-galactose transporter and Acetyl-coA transporters are novel multidrug resistance genes against new classes of antimalarial compounds. Plasmodium
The growing emergence of resistance to anti-infectives is a global problem, threatening to derail disease control programs. Malaria drug resistance is no exception. As new classes of drugs are poised
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Plasmodium falciparum Genome sequencing and assembly Oxoborole Resistance Selection
Plasmodium falciparum parasites resistant to several novel oxoborole small molecules were sequenced to identify resistance-conferring mutations.
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Additional file 9 of Metabolic responses in blood-stage malaria parasites associated with increased and decreased sensitivity to PfATP4 inhibitors
Additional file 9: Table S4. ToxProfiler results (Sheet 1) and expression of Plasmodium genes orthologus to ABCB1 gene (Sheet 2).
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