Adult Connective Tissue-Resident Mast Cells Originate from Late Erythro-Myeloid Progenitors [development]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE119017
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Purpose: The purpose is to systemically identify RNA expression changes along mast cell development during embryogenesis. Methods: We profiled RNA-seq in early EMPs and their progeny. Results: Fetal MCPs acquire the mast cell-specific gene signature from E11.5 and complete their maturation in peripheral tissues. Early EMP-derived MCPs/mast cells and macrophages during embryogenesis were sorted using Csf1r-iCre fate-mapping model and then subjected to RNA-seq.
创建时间：
2019-03-21
