Zizyphus spina christi Effect on Pentylenetetrazole-Induced Kindling

Epilepsy is a common disorder of brain that is not well controlled via drugs available for it.
Gephyrin, a well-known inhibitory synaptic regulator, has a role in epilepsy. Additionally, significant
development of oxidative stresses tends to be involved in epileptic seizure pathophysiology that
giving rise to neuronal cell death. Zizyphus spina christi is a vastly available Iraqi tree and its leaves
have several beneficial effects on central nervous system level.

癫痫是一种常见的脑部疾病，现有药物难以有效控制。Gephyrin，一种广为人知的抑制性突触调节因子，在癫痫中扮演着重要角色。此外，氧化应激的显著发展往往与癫痫发作的病理生理学相关，导致神经元细胞死亡。Zizyphus spina christi是一种在伊拉克广泛分布的树木，其叶具有对中枢神经系统多方面的有益作用。