Structure of a Proline Sulfonamide Inhibitor Bound to HCV NS5b Polymerase
收藏Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/2gc8
下载链接
链接失效反馈官方服务：
资源简介：
Structure of a Proline Sulfonamide Inhibitor Bound to HCV NS5b Polymerase Descriptor: 1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE, RNA-directed RNA polymerase Authors: Gopalsamy, A, Chopra, R, Lim, K, Ciszewski, G, Shi, M, Curran, K.J, Sukits, S.F, Svenson, K, Bard, J, Ellingboe, J.W, Agarwal, A, Krishnamurthy, G, Howe, A.Y, Orlowski, M, Feld, B, O'connell, J, Mansour, T.S. Deposit date: 2006-03-13 Release date: 2006-06-13 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of Proline Sulfonamides as Potent and Selective Hepatitis C Virus NS5b Polymerase Inhibitors. Evidence for a New NS5b Polymerase Binding Site. J.Med.Chem., 49, 2006
创建时间：
2006-03-13
