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Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to compound furan 24

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Protein Data Bank Japan2024-10-23 更新2026-06-30 收录
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Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to compound furan 24 Descriptor: 1-[5-[[3,4-bis(chloranyl)-1~{H}-indol-7-yl]sulfamoyl]-3-methyl-furan-2-yl]carbonyl-~{N}-methyl-piperidine-4-carboxamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ... Authors: Shilliday, F, Lucas, S.C.C, Richter, M, Michaelides, I.N, Fusani, L. Deposit date: 2024-01-12 Release date: 2024-04-03 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders. J.Med.Chem., 67, 2024
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2024-01-12
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