A Regulatory microRNA Network Controls Endothelial Cell Phenotypic Switch During Sprouting Angiogenesis [miRNA-seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE115954
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资源简介：
We exploited a three-dimensional model of sprouting angiogenesis in which the phenotypic switch from quiescent ECs to tip cells was triggered by VEGF-A. The information obtained about modulated miRNAs and their related protein-coding gene targets was used to generate a co-expression network encompassing gene modules that are post-transcriptionally regulated and whose activity is required for sprouting. Gene expression profile study of HUVEC cultured in 3D collagen matrix as quiescent, not-stimulated spheroids (SPHC), and VEGF-A-stimulated sprouted spheroids (SPHV).
创建时间：
2020-02-04
