Cardiac Myofibrillogenesis is Spatiotemporally Modulated by the Molecular Chaperone UNC45B
收藏NIAID Data Ecosystem2026-05-01 收录
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资源简介：
Sarcomeres are fundamental to cardiac muscle contraction. Their impairment can elicit cardiomyopathies, leading causes of death worldwide. However, the molecular mechanism underlying sarcomere assembly remains obscure. We used human embryonic stem cell (hESC)-derived cardiomyocytes (CMs) to reveal step-wise spatiotemporal regulation of core cardiac myofibrillogenesis-associated proteins.
创建时间：
2023-10-24
