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Promotion and maintenance of leukemia by ERG No.1
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创建时间：
2011-04-16
相关数据集
The C-terminus of CBFß-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesis.
The C-terminus of CBFß-SMMHC, the fusion protein produced by a chromosome 16 inversion in acute myeloid leukemia subtype M4Eo, contains domains for self-mulimerization and transcriptional repression,
NIAID Data Ecosystem70
Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [BcorKrasRNA-seq]
Investigation of the transcriptional profile of Bcor?E9-10KrasG12D myeloid progenitors Overall design: Splenocytes from Bcor?E9-10KrasG12D mice were transplanted into PTPRCA recipients, after 4 weeks
NIAID Data Ecosystem50
Systematic screening of chromatin factors identifies divergent roles across haematopoiesis and leukaemia [scRNA-Seq]. Systematic screening of chromatin factors identifies divergent roles across haematopoiesis and leukaemia [scRNA-Seq]
Cellular differentiation-trajectories require extensive alterations in chromatin structure and function, elicited by a diverse array of chromatin-factors (CFs). Using haematopoiesis as a model-system,
NIAID Data Ecosystem50
Inducible PAX5 expression in a human B lymphoblastic leukemia cell line
Hypomorphic mutations of the transcription factor PAX5 occur in one third of B-progenitor acute lymphoblastic leukemias (B-ALLs). To identify PAX5-regulated genes in B-ALL, here we employ inducible ex
NIAID Data Ecosystem60
Genome-wide binding of GFI1 in NB4 cells
ChIP-seq analyses were conducted in NB4 cells with two antibodies against GFI1. Identification of GFI1 binding peaks in acute promyelocytic leukemia derived NB4 cells. Two antibodies against different
NIAID Data Ecosystem50
