Literature phenotypes used to validate the model.

The mutant is defined by perturbations of up to 5 proteins. The phenotype is defined by the cycle stage in question: either metaphase (“Metaphase?” = 1) or anaphase (“Metaphase?” = 0) and spindle aligned (Spindle Aligned? = 1) or misaligned (Spindle Aligned? = 0), and whether Mitotic Exit occurs at this stage. Addtional information on the exact mutant and the literature reference are also included. The column "Simulated mitotic exits” states the number of simulated cells (out of 100) that exited mitosis. The column “Simulated timeouts” states the number of simulated cells (out of 100) that timed out before either a steady state was reached or mitotic exit occurred. The column “Correct?” states whether the simulated phenotype matches the one described in the literature.
(XLSX)