Results of an in silico transcription factor binding motif analysis.

Motives that were enriched in the 1000 bp promoter region upstream of up-regulated lipid related genes are shown on the left, binding motives that were enriched in promoters of down regulated genes on the right and motifs that were associated with up- and down-regulated genes at the bottom. Abbreviations (as used in the Transfac database): AHRARNTHIF: aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator/hypoxia inducible factor, AP1: activator protein 1, AP2: activating protein 2, ATF CREB: activating transcription factor/cAMP response element binding, CHCH: Churchill, CNOT3: CCR4-NOT transcription complex subunit 3, E2F: E2F transcription factor, EGR: early growth response, ELF ETS: E74-like factor/E26 transformation-specific, FKLF: fetal β-like globin gene-activating Krüppel-like factor, FOX: forkhead box, GKLF: gut-enriched Krüppel-like factor, GZF1: GDNF-inducible zinc finger protein 1, HIF2A: hypoxia-inducible factor 2a, IRF: interferon regulatory factor, LXR: liver X receptor, MYCMAX: Myc/Max transcriptional complex, NFY: nuclear factor Y, p53: phosphoprotein p53, PPARG: peroxisome proliferator-activated receptor-gamma, RNF96: RING finger protein 96, SP1SP4: specificity protein 1 and 4, TATA: TATA box, TFE: Transcription Factor E (Family), USF: upstream transcription factor, ZBTB: zinc finger and BTB (broad complex, tramtrack, and bric-à-brac) domain-containing, ZFX: zinc finger X-chromosomal protein, ZNF148: zinc finger protein 148.