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Trimethoprim resistance in E. coli

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NIAID Data Ecosystem2026-05-01 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP325715
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This project involves understanding the genetic determinants of trimethoprim resistance in Escherichia coli using laboratory evolution. E. coli K-12 MG1655 was subjected to 300 ng/ml or 50 ng/mL trimethoprim in a serial passage model for experimental evolution. Resistant clones were isolated on1 microgram/mL trimethoprim. Resistance was also evolved in a Lon-knockout background at 300 ng/mL.
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2023-07-19
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