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Improving the Toolbox of Bioreductions by the Use of Continuous Flow Systems

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Figshare2015-03-01 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Improving_the_Toolbox_of_Bioreductions_by_the_Use_of_Continuous_Flow_Systems/5669371
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Packed bed reactors can be used as an interesting alternative on the bioreduction of β-ketoesteres mediated by immobilized microorganisms. Here in, we report our results on the bioreduction of ethyl 3-oxohexanoate by immobilized Kluyveromyces marxianus cells and tert-butyl 3-oxobutanoate by immobilized Rhodotorula rubra cells under continuous flow conditions leading the desired β-hydroxy esters corresponding in high yields and enantiomeric excess.
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2015-03-01
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