We show that the RNA binding protein Human antigen R is activated in the failing human heart and its inhibition, by genetic deletion or pharmacological inhibition, prevents the progression to heart fa
Data are presented as means ± standard error. Sham: control group; Non-BRL: HF group without BRL37344 injection; BRL: HF group with BRL37344 injection; HR: heart rate; LVESP: left ventricular end-syst
A gene expression topology of the developing, postnatal and diseased heart resulted in re-interpretation of ventricular remodeling in terms of rearrangement of key gene regulatory networks that are im
Neurons exert a pivotal role in the preservation of cardiac physiological function. However, there is a lack of explanation about the mechanism of cardiac neurons in the pathogenesis of cardiac dysfun