HUMAN PI3KGAMMA IN COMPLEX WITH ISOCUMARIN INHIBITOR 11
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HUMAN PI3KGAMMA IN COMPLEX WITH ISOCUMARIN INHIBITOR 11 Descriptor: 3-[(1~{S})-1-[4-azanyl-3-(3-fluoranyl-5-oxidanyl-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-4-phenyl-isochromen-1-one, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION Authors: Pala, D, Bruno, P, Capelli, A.M, Biagetti, M. Deposit date: 2024-08-13 Release date: 2024-12-18 Last modified: 2025-02-26 Method: X-RAY DIFFRACTION (3 Å) Cite: Discovery of CHF-6523, an Inhaled Selective PI3K delta Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease. J.Med.Chem., 68, 2025
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2024-08-13
