Impact of normalization strategies on the similarity of differential miRNA expression of AGL array data.

Agilent - Intra-platform Jaccard index The mean Jaccard indices of significantly regulated miRNA overlap across normalized datasets were depicted for myoblast differentiation and cytokine treated samples analyzed of human and mouse. The Jaccard index ranges between zero and one per definition. The closer the Jaccard index is to one the higher the relative similarity and reproducibility of differential expression across platforms.