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Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts

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NIAID Data Ecosystem2026-03-13 收录
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To confirm the negative crosstalk with SUMO in human cells, linear non-hydrolyzable genetic fusions of SUMO-H4 were generated in HEK293T cells and analyzed by western blotting and chromatin immunoprecipitation followed by high-throughput sequencing of the associated DNA (ChIP-seq).

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2021-10-14
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