Crystal structure of TrkA in complex with PF-00593174
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Crystal structure of TrkA in complex with PF-00593174 Descriptor: High affinity nerve growth factor receptor, N-{4-[4-amino-7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-2-yl}-N'-(2,4-difluorophenyl)urea Authors: Jayasankar, J, Brown, D, Skerratt, S, Kurumbail, R. Deposit date: 2016-04-19 Release date: 2017-03-01 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.07 Å) Cite: The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain. J. Med. Chem., 59, 2016
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2016-04-19
