The "source dat.zip" file contains the raw data underlying the graphs in the main manuscript and Supplementary Information. All the data are included in the directories "fig xxx". The input files of M

Figshare2026-03-28 更新40

The Membrane-Proximal Stem Region of Vesicular Stomatitis Virus G Protein Confers Efficient Virus Assembly

病毒组装机制

膜蛋白功能分析

In this report, we show that the glycoprotein of vesicular stomatitis virus (VSV G) contains within its extracellular membrane-proximal stem (GS) a domain that is required for efficient VSV budding. T

PubMed Central40

A focused deep mutational scan on the Env transmembrane and proximal cytosolic regions reveals an absence of sequence features for MA association. A focused deep mutational scan on the Env transmembrane and proximal cytosolic regions reveals an absence of sequence features for MA association

病毒组装机制

蛋白质深度突变扫描

The HIV-1 surface glycoprotein Env binds target receptors to mediate fusion of the viral and host cell membranes during infection. Env is incorporated with very low density into virions, and in some c

NIAID Data Ecosystem60

Structure of a Novel Shoulder-to-Shoulder p24 Dimer in Complex with the Broad-Spectrum Antibody A10F9 and Its Implication in Capsid Assembly

HIV-1衣壳结构

蛋白二聚化机制

Mature HIV-1 viral particles assemble as a fullerene configuration comprising p24 capsid hexamers, pentamers and dimers. In this paper, we report the X-ray crystal structures of the p24 protein from n

Figshare2016-01-18 更新40