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Genome-wide analysis of SIK2 regulated genes and pathways. Homo sapiens

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA195915
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Identification of SIK2 regulated genes and pathways after SIK2 knock-down and overexpression of a wild-type and kinase-dead SIK2. The hypothesis is that SIK2 regulated gene expression via CREB1 Overall design: Total RNAs were obtained after SIK2 gene was knocked down with siRNA and after a wild-type SIK2 or a kinase-dead SIK2 construct were over-expressed in LNCaP cells. A control where the cells were treated with a CREB1 inducer (Forskolin) was also included.
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2013-04-02
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