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Human Arginase1 Complexed with Bicyclic Inhibitor Compound 13

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Human Arginase1 Complexed with Bicyclic Inhibitor Compound 13 Descriptor: Arginase-1, MANGANESE (II) ION, {3-[(5R,7S,8S)-8-azaniumyl-8-carboxy-2-azaspiro[4.4]nonan-2-ium-7-yl]propyl}(trihydroxy)borate(1-) Authors: Palte, R.L, Lesburg, C.A. Deposit date: 2019-12-08 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. Acs Med.Chem.Lett., 11, 2020

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2019-12-08
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