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Crystal structure of human DNA polymerase eta in ternary complex with a cisplatin DNA adduct

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Crystal structure of human DNA polymerase eta in ternary complex with a cisplatin DNA adduct Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*TP*GP*GP*TP*CP*TP*CP*CP*TP*CP*C)-3', 5'-D(*TP*GP*GP*AP*GP*GP*AP*GP*A)-3', ... Authors: Ummat, A, Rechkoblit, O, Jain, R, Choudhury, J.R, Johnson, R.E, Silverstein, T.D, Buku, A, Lone, S, Prakash, L, Prakash, S, Aggarwal, A.K. Deposit date: 2012-03-28 Release date: 2012-05-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Structural basis for cisplatin DNA damage tolerance by human polymerase {eta} during cancer chemotherapy. Nat.Struct.Mol.Biol., 19, 2012
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2012-03-28
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