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Crystal Structure of KDM4A with compound YP-02-145

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Protein Data Bank Japan2024-01-31 更新2026-03-21 收录
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Crystal Structure of KDM4A with compound YP-02-145 Descriptor: 1,2-ETHANEDIOL, 2-(3-methyl-5-oxidanylidene-4-phenyl-4~{H}-pyrazol-1-yl)-3~{H}-benzimidazole-5-carboxylic acid, CITRIC ACID, ... Authors: Malecki, P.H, Carter, D.M, Gohlke, U, Specker, E, Nazare, M, Weiss, M.S, Heinemann, U. Deposit date: 2018-03-30 Release date: 2019-04-10 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer. J.Med.Chem., 64, 2021
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2018-03-30
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