Significant median differences (MD), confidence intervals (CI) and P-values (p) for cytokine levels in active TB compared to controls and LTBI after stimulation with CFP-10 and ESAT-6.
Tuberculosis (TB) causes an estimated 2 million people per year globally. However, despite technological advances of the 21st century, there are no efficacious vaccines that prevent TB transmission. T
Footnotes: TB: tuberculosis; HIV: human immunodeficiency virus; n/N = number of positive tests/number of tested sera in each group; TST: tuberculin skin test (cut-off 5 mm); Cut-off value for PGL-Tb1:
A blood transcriptome analysis was performed on a set of healthy subjects and patients infected with M. africanum (MAF) or M. tuberculosis (MTB). All study participants were recruited from Mali. Overa