Gene expression analysis of transplanted wt and Matn4-/- hematopoietic stem cells (HSC)

This study aimed at identifying the differences in expression levels between wt and Mant4-/- HSCs after transplantation, to determine the mechanism through which Mant4-/- gain a proliferative advantage. mRNA expression was analyzed from Matn4-/- and wt HSCs isolated 4 weeks after transplantation into lethally irradiated recipients. 3 biological replicates were used per group.