Direct Observation of Competing PrP Fibril Populations with Distinct Structures and Kinetics

NIAID Data Ecosystem2026-03-13 收录

朊病毒蛋白纤维化

蛋白质聚集动力学

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MATLAB scripts used in paper: Direct Observation of Competing PrP Fibril Populations with Distinct Structures and Kinetics

创建时间：

2022-08-05

Dynamics of oligomer and amyloid fibril formation by yeast prion Sup35 observed by high-speed atomic force microscopy. Konno et al.

蛋白质聚集动力学

淀粉样蛋白纤维

Source data for “Dynamics of oligomer and amyloid fibril formation by yeast prion Sup35 observed by high-speed atomic force microscopy" (Konno et al.)

NIAID Data Ecosystem90

Mass-Spectrometry-Based GEE Footprinting Characterizes Kinetic Mechanisms and Sites of Conformational Change in Amyloid β 1–42 Aggregation

蛋白质聚集动力学

阿尔茨海默病病理学

Understanding the dynamics of Aβ aggregation is critical for elucidating Alzheimer’s disease (AD) progression. This study extends our previous work on Aβ42 using fast photochemical oxidation of protei

Figshare2025-05-16 更新30

Digital data deposition and Matlab fitting scripts for the paper entitled "Quantitative NMR analysis of the mechanism and kinetics of chaperone Hsp104 action on amyloid-b42 aggregation and fibril formation"

蛋白质聚集动力学

核磁共振数据

1. All Matlab scripts used to fit the data for aggregation of amyloid Ab42 over a wide range of Hsp104 concentrations as monitored by the decay of monomer NMR intensity 2. Average intensities over 21

Figshare2023-05-03 更新20

Protein Aggregation: Kinetics versus Thermodynamics

蛋白质聚集动力学

分子动力学模拟

In this study, we address the questions of how important is the kinetics in protein aggregation, and what are the intrinsic properties of proteins that cause this behavior. On the basis of our recent

NIAID Data Ecosystem60

Kinetic parameters for the growth of ThT fluorescence intensity of mutants inserted by different number of glutamines into Tau244–372/ΔPHF6/ΔPHF6*.

蛋白质聚集动力学

tau蛋白结构

Best-fit values of these kinetic parameters were derived from non-linear least squares modeling of the Hill equation to the experimental data. The concentration of Tau protein was 20 µM, and 20 mM NaH

Figshare2015-12-02 更新20

Direct Observation of Competing PrP Fibril Populations with Distinct Structures and Kinetics

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