Indium-Promoted Diastereoselective Addition of Fluorinated Haloallylic Derivatives to Imines

We report herein the first general
access to fluorinated homoallylic amines by means of an addition of
fluorinated organoindium reagent. The corresponding amines were obtained
in good to excellent yield with excellent diastereoisomeric ratio.
A plausible mechanism is proposed to explain the stereochemical outcome
of the reaction based on the X-ray structure of the products.