Bioactive Myrsinol Diterpenoids from the Roots of <i>Euphorbia prolifera</i>
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Ten myrsinol diterpenes, euphorbiaproliferins A–J (1–10), along with nine known analogues (11–19) were isolated from the roots of Euphorbia prolifera. Their structures were elucidated by spectroscopic data analysis (IR, ESIMS, HRESIMS, 1D and 2D NMR), and the structure of 1 was confirmed by X-ray crystallography. The diterpenes showed neuroprotective effects against MPP+-induced neuronal cell death in SH-SY5Y cells.
创建时间:
2016-02-22



