首页/数据集/Inhibitors of 4-Phosphopanthetheine Adenylyltransferase

Inhibitors of 4-Phosphopanthetheine Adenylyltransferase

NIAID Data Ecosystem2026-05-01 收录

抗菌药物发现

抑制剂筛选

数据链接：

https://www.rcsb.org/structure/4NAT 数据链接链接失效反馈

官方服务：

资源简介：

Inhibitors of 4-Phosphopanthetheine Adenylyltransferase

应用场景：

创建时间：

2024-02-28

靶向抗肿瘤药物设计

抑制剂筛选

Heparanase is the sole mammalian enzyme capable of cleaving glycosaminoglycan heparan sulfate side chains of heparan sulfate proteoglycans. Its altered activity is intimately associated with tumor gro

NIAID Data Ecosystem90

Activity comparison for TBK1 and IKKε.

抑制剂筛选

药物发现

Number of active compounds (N) detected in each screen for total number detected (unfiltered), number after drug like filtering (filtered.drug-like), hits from the LOPAC and Kinase libraries, and the

NIAID Data Ecosystem50

U2OS cell line -SpCas9 inhibitor- Raw sequence reads

CRISPR-Cas9基因编辑

抑制剂筛选

To detect the cleavage activity of SpCas9 in U2OS after treat with small molecular inhibitor of SpCas9

NIAID Data Ecosystem30

Supplemental Table S3 from High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma

肉瘤靶向治疗

抑制剂筛选

Supplemental Table S3. Target sequences for shRNAs targeting AURKB expression in the in vivo dependency screen

NIAID Data Ecosystem80

Novel bacterial methionine aminopeptidase inhibitors