Identification of novel amrR deletions as meropenem resistance mechanisms in clinical Burkholderia pseudomallei isolates

To investigate the mechanisms of MEM resistance in B. pseudomallei. We conducted mutagenesis and reverse transcription polymerase chain reaction (qRT-PCR) on three MEM-LS strains to elucidate the role of these partial deletions in the amrR gene in B. pseudomallei's reduce susceptibility to MEM.