Transcriptional analysis of Streptococcus mutans cultures treated with MUC5B mucin and glycans

Supplementary Table 1. Transcriptional analysis of cultures treated with 0.1% MUC5B Mucin, 0.1% MUC5B Glycans, and 0.1% MUC5AC glycans. S. mutans UA159 was grown into mid-exponential phase in CMedia. Supplementary Table 2. Pathway Enrichment Analysis based on KEGG. Genes with an FDR less than 0.05 were considered significantly changed. “Background” indicates the number of genes that are annotated as being involved in the pathway. “Input” indicates the number of genes that were significantly changed upon exposure to MUC5B Mucin, MUC5B Glycans, or MUC5AC Glycans belong to the pathway.Data from Werlang, C.A., Chen, W.G., Aoki, K. et al. Mucin O-glycans suppress quorum-sensing pathways and genetic transformation in Streptococcus mutans. Nat Microbiol 6, 574–583 (2021).