Characteristics of long non-coding RNAs in the pancreas of rats with acute pancreatitis

This study aimed to describe the microarray-based differential expression profile of mRNAs and lncRNAs in acute experimental pancreatitis and identify candidate biomarkers for the diagnosis, prognosis, and treatment of AP. A rat model of AP was generated with retrograde pancreatic ductal injection of sodium taurocholate, and the pancreas was harvested for microarray detection. The biological functions of differentially expressed genes noted from microarray data were assessed by bioinformatics analysis.