KEGG Pathway Database (Kanehisa, 2019; Kanehisa et al., 2025; Kanehisa & Goto, 2000) was used to collect genes on insulin signaling, lipid metabolism and inflammation pathways, underlying metaboli
The prevalence and healthcare burden of obesity and its related metabolic disorders such as type 2 diabetes (T2D) are increasing rapidly. A better understanding of the pathogenesis of these diseases h
